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Breakthroughs in clinical epigenetics
Genome-wide association studies are no longer expected to yield the markers to fully explain the heritable susceptibility observed for many complex diseases. This realization has sparked an interest in...
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The Epigenetics and Chromatin Clinic
During the recent American Society of Human Genetics (#ASHG15) conference I met with Dr Hans T Bjornsson, who is Director of the Epigenetics and Chromatin Clinic at Johns Hopkins University School of...
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Do stress factors alter DNA methylation during aging?
What is meant by epigenetic aging? Epigenetic aging is a measure that uses DNA methylation levels to predict an individual’s age. It takes into account the methylation levels of many sites from...
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Why do we age (part 4): epigenetics and a calorie restriction diet
What everyone wants is to live a long life. However, whilst already living longer, we have realized that longevity is of little value when associated with diseases and disability. As a result, we...
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The future of epigenetic drugs
In recent years, research efforts in this area have grown substantially to uncover the biological and chemical mechanisms of epigenetic drugs and their targets. At the same time, pharmaceutical...
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Biomarkers of aging from epigenetic clocks
We use clocks to keep track of time. When it comes to the term ‘clock’, I think of the hour glass on my dresser, the pendulum clock in my living room, my first wristwatch that I was so excited to get...
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Fascinating Plant Epigenomes
Epigenetics refers to mechanisms that affect gene activity and expression without a change to the DNA sequence. Epigenetic processes are important in both plants and animals, but plants are...
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Paternal genome elimination: investigating a strange reproductive strategy
Genomic imprinting is a phenomenon in which the expression of a gene depends on its parental origin, hence expression is said to be parent-of-origin specific. This process is independent of the laws of...
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Could new epigenetic cancer treatments be impacting the future offspring?
Advances in diagnostics and therapeutics in cancer research have allowed doctors to catch and treat cancer earlier, thus resulting in better prognoses in many cases. However, this also means that a...
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The epigenetics diet: A barrier against environmental pollution
Early-life dietary nutrition can profoundly affect individual developmental fate and disease prevention. For example, the presence of absence of royal jelly determines whether the larvae of female...
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